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GH Fragment is the modified form of amino acids 176-191 of the growth hormone peptide. It is a 15-mer peptide residue of the C-terminus of HGH to which tyrosine is added at the N-terminal end.
The FRAG 176-191 is a stabilized analogue of the growth hormone-releasing factor (GRF) that induces growth hormone (GH) in a specific and physiological manner. To date studies suggest that (HGH fragment 176-191) has several beneficial features: it reduces abdominal fat (in particular visceral fat), without compromising glycemic control (blood glucose), it increases muscle mass and improves the lipid profile. These characteristics make it an ideal candidate for the treatment of excess abdominal fat, an important aspect of HIV-associated lipodystrophy.